Patient Portrayal

Traveling with ULCERATIVE COLITIS OR CROHN'S DISEASE

Traveling can be exciting, but if you live with moderate to severe ulcerative colitis (UC) or Crohn's disease, then it may require some additional planning. If you plan on being away from home at the time of your next dose, use the steps below to prepare accordingly.

Traveling within the United States if you're receiving infusions

Please notify your healthcare provider of your travel as soon as possible.
Find an infusion center when you are traveling.
- Ask your doctor for a referral to an infusion center.
- Call EntyvioConnect at 1-844-ENTYVIO and we'll help you find an infusion center
- Search for an infusion center
It is recommended to have your healthcare provider give you a written plan of action in case of an emergency.

Traveling outside the United States if you're receiving infusions

Please notify your healthcare provider of your travel as soon as possible.
If you have US-based health insurance, contact EntyvioConnect at 1-844-ENTYVIO (1-844-368-9846) and ask if ENTYVIO is approved for use in your destination country. EntyvioConnect will call your insurance provider to determine your coverage and restrictions while abroad.
Work with your healthcare provider and insurance company to identify an infusion center. EntyvioConnect will not be able to locate an infusion center outside the United States.
It is recommended to have your healthcare provider give you a written plan of action in case of an emergency.

Traveling with the ENTYVIO Pen

If needed, the ENTYVIO Pen can be left out of the refrigerator in original package at room temperature up to 77°F (25°C) for up to 7 days (for example, when traveling). Do not use the ENTYVIO Pen if left out of the refrigerator for more than 7 days.
Do not freeze the ENTYVIO Pen, and do not use it if it has been frozen.
Do not shake the ENTYVIO Pen.
Retain in the original package to protect from light until the time of use.
If traveling outside the United States, it is recommended that you carry a copy of your prescription for the ENTYVIO Pen.

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IMPORTANT SAFETY INFORMATION

Do not receive ENTYVIO^® if you have had an allergic reaction to ENTYVIO or any of its ingredients.
ENTYVIO may cause serious side effects, including:
- Infusion-related and serious allergic reactions can happen while you are receiving ENTYVIO or several hours after treatment. You may need treatment if you have an allergic reaction. Tell your healthcare provider or get immediate medical help if you get any of these symptoms during or after an infusion of ENTYVIO: rash, itching, swelling of your lips, tongue, throat or face, shortness of breath or trouble breathing, wheezing, dizziness, feeling hot, or palpitations (feel like your heart is racing).
- Infections. ENTYVIO may increase your risk of getting a serious infection. Before receiving and during treatment with ENTYVIO, tell your healthcare provider if you think you have an infection or symptoms of an infection, such as fever, chills, muscle aches, cough, shortness of breath, runny nose, sore throat, red or painful skin or sores on your body, tiredness, or pain during urination.
- Progressive Multifocal Leukoencephalopathy (PML). People with weakened immune systems can get progressive multifocal leukoencephalopathy (PML) (a rare, serious brain infection caused by a virus). Although unlikely while receiving ENTYVIO, a risk of PML cannot be ruled out. PML can result in death or severe disability. There is no known treatment, prevention, or cure for PML. Tell your healthcare provider right away if you have any of the following symptoms: confusion or problems thinking, loss of balance, change in the way you walk or talk, decreased strength or weakness on one side of the body, blurred vision, or loss of vision.
- Liver problems can happen in people who receive ENTYVIO. Tell your healthcare provider right away if you have any of the following symptoms: tiredness, loss of appetite, pain on the right side of your abdomen, dark urine, or yellowing of the skin and eyes (jaundice).
The most common side effects of ENTYVIO include: common cold, headache, joint pain, nausea, fever, infections of the nose and throat, tiredness, cough, bronchitis, flu, back pain, rash, itching, sinus infection, throat pain, pain in extremities, and with injections under the skin: pain, swelling, itching, hives, bruising, rash, or redness at the injection site. These are not all the possible side effects of ENTYVIO. Call your healthcare provider for medical advice about side effects.
Before receiving ENTYVIO, tell your healthcare provider about all of your medical conditions, including if you: have or think you may have an infection or have infections that keep coming back; have liver problems; have tuberculosis (TB) or have been in close contact with someone with TB; have recently received or are scheduled to receive a vaccine; or if you are pregnant, breastfeeding, plan to become pregnant, or plan to breastfeed.
Tell your healthcare provider about all the medicines you take, especially if you take or have recently taken Tysabri (natalizumab), Tyruko (natalizumab-sztn), a Tumor Necrosis Factor (TNF) blocker medicine, a medicine that weakens your immune system (immunosuppressant), or corticosteroid medicine.

Please see accompanying full Prescribing Information, including the Medication Guide, for ENTYVIO and talk with your healthcare provider.

ENTYVIO is available for:

intravenous (IV) infusion: 300 mg vedolizumab.
subcutaneous (SC) injection: 108 mg vedolizumab.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-10881-800-FDA-1088.

What is ENTYVIO (vedolizumab)?

ENTYVIO is a prescription medicine used in adults for the treatment of:

moderately to severely active ulcerative colitis (UC).
moderately to severely active Crohn’s disease (CD).

It is not known if ENTYVIO is safe and effective in children under 18 years of age.

Important Safety Information

Do not receive ENTYVIO^® if you have had an allergic reaction to ENTYVIO or any of its ingredients.

ENTYVIO may cause serious side effects, including:

Infusion-related and serious allergic reactions can happen while you are receiving ENTYVIO or several hours after treatment. You may need treatment if you have an allergic reaction. Tell your healthcare provider or get immediate medical help if you get any of these symptoms during or after an infusion of ENTYVIO: rash, itching, swelling of your lips, tongue, throat or face, shortness of breath or trouble breathing, wheezing, dizziness, feeling hot, or palpitations (feel like your heart is racing).
Infections. ENTYVIO may increase your risk of getting a serious infection. Before receiving and during treatment with ENTYVIO, tell your healthcare provider if you think you have an infection or symptoms of an infection, such as fever, chills, muscle aches, cough, shortness of breath, runny nose, sore throat, red or painful skin or sores on your body, tiredness, or pain during urination.
Progressive Multifocal Leukoencephalopathy (PML). People with weakened immune systems can get progressive multifocal leukoencephalopathy (PML) (a rare, serious brain infection caused by a virus). Although unlikely while receiving ENTYVIO, a risk of PML cannot be ruled out. PML can result in death or severe disability. There is no known treatment, prevention, or cure for PML. Tell your healthcare provider right away if you have any of the following symptoms: confusion or problems thinking, loss of balance, change in the way you walk or talk, decreased strength or weakness on one side of the body, blurred vision, or loss of vision.
Liver problems can happen in people who receive ENTYVIO. Tell your healthcare provider right away if you have any of the following symptoms: tiredness, loss of appetite, pain on the right side of your abdomen, dark urine, or yellowing of the skin and eyes (jaundice).

The most common side effects of ENTYVIO include: common cold, headache, joint pain, nausea, fever, infections of the nose and throat, tiredness, cough, bronchitis, flu, back pain, rash, itching, sinus infection, throat pain, pain in extremities, and with injections under the skin: pain, swelling, itching, hives, bruising, rash, or redness at the injection site. These are not all the possible side effects of ENTYVIO. Call your healthcare provider for medical advice about side effects.

Before receiving ENTYVIO, tell your healthcare provider about all of your medical conditions, including if you: have or think you may have an infection or have infections that keep coming back; have liver problems; have tuberculosis (TB) or have been in close contact with someone with TB; have recently received or are scheduled to receive a vaccine; or if you are pregnant, breastfeeding, plan to become pregnant, or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, especially if you take or have recently taken Tysabri (natalizumab), Tyruko (natalizumab-sztn), a Tumor Necrosis Factor (TNF) blocker medicine, a medicine that weakens your immune system (immunosuppressant), or corticosteroid medicine.

Please see accompanying full Prescribing Information, including the Medication Guide, for ENTYVIO and talk with your healthcare provider.

ENTYVIO is available for:

intravenous (IV) infusion: 300 mg vedolizumab.

subcutaneous (SC) injection: 108 mg vedolizumab.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-10881-800-FDA-1088.

What is ENTYVIO (vedolizumab)?

ENTYVIO is a prescription medicine used in adults for the treatment of:

moderately to severely active ulcerative colitis (UC).

moderately to severely active Crohn’s disease (CD).

It is not known if ENTYVIO is safe and effective in children under 18 years of age.

Traveling with ULCERATIVE COLITIS OR CROHN'S DISEASE

Traveling within the United States if you're receiving infusions

Traveling outside the United States if you're receiving infusions

Traveling with the ENTYVIO Pen

Get treatment reminders

Find an infusion center

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